Pre-radiation chemotherapy with BCNU and cisplatinum in the initial management of patients with malignant glioma.

Patients receive 3 courses of this combination chemotherapy regimen via a continuous infusion over a 3-day period. This is then followed by conventional radiation therapy and, if appropriate, a stereotactic radiosurgery boost with the Gamma Knife.

Pre-Radiation Chemotherapy For Pure And Mixed Oligodendrogliomas

Patients receive 3 courses of this combination chemotherapy regimen via a continuous infusion over a 3-day period. This is then followed by conventional radiation therapy.

"Phase 3 Intergroup Randomized Comparison Of Radiation Alone Vs. Pre-Radiation Chemotherapy For Pure And Mixed Anaplastic Oligodendrogliomas" (RTOG 00-00)

Patients receive 3 courses of this combination chemotherapy regimen via a continuous infusion over a 3-day period. This is then followed by conventional radiation therapy.